… of the rationale for developing radiolabeled sdAbs for RPT … the ratio of internalized fraction
over surface bound fraction, … which has incorporated several distinguishing design features: a …

… bound) is usually utilized to identify the cellular uptake of … to injection with the radiolabelled
antibody. Eventually this has … the total cell binding capacity (internalized and surface bound) …

… of the adaptive immune system to recognize and neutralize … (169) After surface-bound
antibodies capture C1q, a cascade … to the internalization and elimination of antibodies should also …

… cell surface bound EVs prior to imaging the cells. At 37 C, PKH26-labeled EVs internalized
into cells … methodology remains relevant to evaluate any potential EV biocorona differences. …

… 3d, blue surface) and overlap with the surface bound by EGF (Fig… -158 triggers EGFR
internalization and degradation in an … . The immunoreactivity of the antibody after radiolabeling …

… The only difference lies in the chelating agent for zirconium … radiolabeling procedure was
performed by adjusting the pH of … glycine (surface-bound), and 1 M NaOH (internalized fraction) …

… FAPα, which is a cell surface-bound type II transmembrane … analysis, except a slight difference
between the uptake values of … with no internalization that limits their function for efficient …

… recover the surface-bound [ 89 Zr]Zr-DFO-2Rs15d, cells were … The BT474 cells were
used to determine the internalization of [ … 2Rs15d can potentially be used to identify HER2-positive …

… in this work—which provides further advantages for this product [25]. … In addition, in this case,
no significant difference was … and was internalized into the tumor cells according to in vitro …

… conditions to avoid the loss of surface-bound molecules. The … only by internalized
nanocarriers, the cell supernatants were … We utilized a ROUT test to identify outliers. In case of …